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Chicken Bubble Biscuit Bake Casserole Recipe

4.6 from 109 reviews

This Chicken Bubble Biscuit Bake Casserole is a comforting and easy-to-make dish featuring tender cooked chicken mixed with creamy soup, sour cream, and vegetables, all enveloped by fluffy biscuit dough and topped with melted cheese. Baked to golden perfection, it’s a perfect hearty meal for family dinners or gatherings.

Ingredients

Scale

For the Filling

  • 2 cups cooked chicken, shredded or diced (rotisserie works great)
  • 1 (10.5 oz) can cream of chicken soup (or cream of mushroom)
  • 1/2 cup sour cream or plain Greek yogurt
  • 1/2 cup milk
  • 1 cup frozen mixed vegetables (peas, carrots, corn, beans)
  • 1 tsp garlic powder
  • 1/2 tsp onion powder
  • Salt & pepper to taste

For the Topping

  • 1 (16 oz) can refrigerated biscuit dough, cut into quarters
  • 1 cup shredded cheddar cheese or mozzarella
  • 1 tbsp melted butter (optional, for brushing)

Instructions

  1. Preheat Oven: Preheat your oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish to prevent sticking.
  2. Mix the Filling: In a large bowl, combine the cooked shredded or diced chicken, cream of chicken soup, sour cream or Greek yogurt, milk, frozen mixed vegetables, garlic powder, onion powder, salt, and pepper. Stir well until the mixture is smooth and fully combined.
  3. Add Biscuits: Fold the quartered biscuit pieces into the chicken filling mixture, ensuring the biscuits are well coated with the creamy blend.
  4. Assemble Casserole: Pour the entire mixture into the prepared baking dish, spreading it out evenly. Sprinkle shredded cheddar or mozzarella cheese evenly over the top for a melty, cheesy finish.
  5. Bake Covered: Cover the dish tightly with foil and bake in the preheated oven for 20 minutes to allow the biscuits to start cooking through.
  6. Finish Baking: Remove the foil and continue baking for an additional 10 to 15 minutes, or until the biscuits are puffed, golden brown, and fully cooked.
  7. Optional Butter Brush & Serve: If desired, brush the top with melted butter for extra richness. Allow the casserole to cool slightly before serving to set.

Notes

  • You can use any cooked chicken such as rotisserie or leftover chicken breast.
  • Substitute cream of chicken soup with cream of mushroom for a different flavor.
  • Frozen mixed vegetables can be adjusted based on preference or availability.
  • Use sour cream or Greek yogurt depending on your preference for tanginess and creaminess.
  • For a crispier biscuit topping, skip covering the dish with foil initially or bake uncovered for the last 15 minutes.
  • This casserole can be prepared a day ahead and refrigerated before baking.

Keywords: Chicken casserole, biscuit bake, comfort food, easy dinner, cheesy chicken bake, one-dish meal